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    invitrogen Mouse T-Activator CD3/CD28(11456d)

    • 產(chǎn)品型號:
    • 產(chǎn)品時間:2024-08-08
    • 簡要描述:慧穎生物專業(yè)供應(yīng)Dynabeads® Mouse T-Activator CD3/CD28 for T-Cell Expansion and Activation;From 100- to 1000-fold T cell expansion,Store at: 2–8°C。慧穎訂購: 。
    • 產(chǎn)品簡介

    invitrogen Mouse T-Activator CD3/CD28 for T-Cell Expansion and Activation
    貨號:貨號11456D  包裝0.4 ml  市場價格:1204元
    貨號:貨號11452D  包裝2 ml  市場價格:6130
    慧穎生物
    *,原裝正品,貨源穩(wěn)定,價格公道
    全國訂購:/8 !
    訂購
    Description
    Dynabeads® Mouse T-Activator CD3/CD28 is for the activation and expansion of mouse T cells for research purposes.
    With Dynabeads® Mouse T-Activator CD3/CD28 you get:
    1)Activation of T cells without the need of feeder cells
    2)Activated cells that retain in vivo-like function
    3)Maximal reproducibility without contamination by soluble antibodies or mitogens
    4)From 100- to 1000-fold T cell expansion
    How Dynabeads® Mouse T-Activator CD3/CD28 works:
    Dynabeads® Mouse T-Activator CD3/CD28 offers a simple method for activation and expansion of T cells that does not require feeder cells (antigen-presenting cells) or antigen. The 4.5 µm diameter, inert, superparamagnetic beads are similar in size to antigen-presenting cells, and are covalently coupled to anti-CD3 and anti-CD28 antibodies. These two antibodies provide primary and co-stimulatory signals, optimized for efficient T-cell activation and expansion. Expansion of the T-cell population can be stimulated using recombinant IL-2, and View Moreafter activation or expansion, the magnetic beads can be easily removed using a DynaMag™ magnet.
    For expansion of antigen specific T cells from T cell clones or T cell lines, we recommend using Dynabeads® Mouse T-Activator CD3/CD28/CD137.
    Starting samples
    Start with single cell suspensions from spleen or lymph nodes, mononuclear cells (MNCs), whole blood, or T cell subsets including CD3+ T cells, CD4+ or CD8+ T cells, or regulatory T cells. For an overview over the different Dynabeads® available for cell isolation, look here.

    Downstream applications
    The activated T cells can be analyzed shortly after activation (for transfection/transduction or to study TCR signaling, proteomics, gene expression, etc.). T cells can be left in culture to differentiate into T helper cell subsets or expansion of polyclonal/antigen-specific T cells.
    For research use only. Not for use in diagnostic procedures.
    Contents and Storage
    Dynabeads® Mouse T-Activator CD3/CD28 are supplied as a suspension containing 4 × 107 Dynabeads®/ml in phosphate buffered saline (PBS), pH 7.4, with 0.1% bovine serum albumin (HSA). Store at: 2-8°C.

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